Gimnich OA, Holbrook J, Belousova T, et al. - Researchers assumed that contrast-enhanced magnetic resonance imaging (CE-MRI) based arterial signal enhancement measures are correlated with markers of peripheral artery disease (PAD). This study included a sum of 66 participants, 10 were excluded due to incomplete data, resulting in 56 participants for the final analyses (36 PAD, 20 matched controls). The bilateral thigh blood-pressure cuffs were applied to conduct MR imaging post reactive hyperemia. In comparison with matched controls, CE-MRI first-pass arterial perfusion is impaired in PAD patients and correlated with markers of lower extremity ischemia.