Herrera C, Bruña V, Abizanda P, et al. - The link between atrial fibrillation, stroke, and interatrial block (IAB) (P-wave duration ≥ 120 ms) is well known, especially in the case of advanced IAB, so researchers explored if there is any correlation between IAB and mild cognitive impairment. Advanced Characterization of Cognitive Impairment in Elderly with Interatrial Block was a case-control multicenter study, including patients aged ≥ 70 years in sinus rhythm with no significant structural heart disease. In total, 265 individuals, 143 cases with mild cognitive impairment and 122 controls with normal cognitive function, with a mean age of 79.6 ± 6.3 years were involved. Cases had longer P-wave duration, higher prevalence of IAB, higher prevalence of advanced IAB, and higher MVP ECG risk score vs controls. In individuals aged ≥ 70 years without significant structural heart disease, IAB is independently linked to mild cognitive impairment. In the case of advanced IAB, this connection is stronger.