Relation of cardiovascular events and deaths to low-density lipoprotein cholesterol level among statin-treated patients with atherosclerotic cardiovascular disease
The American Journal of Cardiology May 13, 2019
Chamberlain AM, et al. - Among 1,854 patients (mean [SD] age 66.0 [13.3] years, 63.6% male) receiving moderate- to high-intensity statins for atherosclerotic cardiovascular disease (ASCVD: myocardial infarction, unstable angina, coronary revascularization, ischemic stroke or transient ischemic attack), researchers assessed ensuing cardiovascular events and mortality according to low-density lipoprotein cholesterol (LDL-C) level. The participants were residents of Olmsted County, MN and were followed up for a median of 5.9 years. According to the findings, a high rate of ensuing cardiovascular events was noted in patients with ASCVD; patients with LDL-C ≥100 mg/dl showed the highest rates, indicating that, even in patients receiving moderate- to high-intensity statins, treatment needs are still not being met.
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