Guenego A, et al. - Researchers analyzed a large French prospective cohort to determine the potential associations between history of hysterectomy, with or without oophorectomy, and history of benign gynecological disease (uterine fibroids, endometriosis) and the incidence of differentiated thyroid cancer. They followed-up with 89,340 women from the E3N cohort between 1990 and 2012. Findings revealed an increased risk of differentiated thyroid cancer among women who had either a history of fibroids or hysterectomy. Findings thereby indicate shared biological mechanisms between fibroids and thyroid cancer, which warrant further investigation. Risk of thyroid cancer showed no correlation with endometriosis, uterine polyps, ovarian cysts and oophorectomy without hysterectomy.