Wertheimer CM, Brandt K, Kaminsky S, et al. - In the present study, the researchers sought to assess a new non-ablative and adjustable procedure for laser ablative refractive corneal surgery in hyperopia utilizing the injection of a biocompatible liquid filler material into a stromal pocket. Using a clinical femtosecond laser system, a total of 120 stromal pockets were created in 96 rabbit corneoscleral discs and 24 whole globes. A steepening of the anterior and flattening of the posterior corneal surface was observed after injection, which resulted in hyperopic correction. The pocket depth and the injected volume were the two main factors determining the amount of correction. Following the homogeneous filling of the pocket, an initial refractive increase was observed, followed by a linear relationship between the injected volume and the refraction increase. This possible clinical protocol for controlled hyperopia refraction correction indicates a potential readjustable clinical application.