Luong J, et al. - In view of the common occurrence of lymphocele in sentinel node biopsy (SNB) for melanoma, researchers examined if the intraoperative placing of plant-based hemostatic powder (PBHP) could reduce lymphocele rates. In this open label, prospective, IRB -approved, before- and-after, matched control trial, they placed PBHP into the wound in patients undergoing SNB of groin or axillary nodes for melanoma staging. In 61 and 55 patients, they performed 66 control and 66 treatment (49 axillary and 17 groin in each arm) SNBs, respectively, for a total 132 SNBs in 116 patients. Outcomes revealed a decreased rate of lymphoceles with intra-operative placement of PBHP in these patients.