Mian S, et al. - Researchers intended to appraise whether a relationship between RM and back pain existed, via systematic review and meta-analysis. The review gave 13 articles following exclusions, eight of which were appropriate for quantitative analysis. Across all studies, the outcomes of the analysis proposed betterment in back pain after reduction mammoplasty (RM). Moreover, heterogeneity was high. However casual, the evidence obtained implies that in individuals with large breasts, RM decreases the incidence of back pain. Moreover, the shortage of studies examining whether RM is at the clinical threshold of efficiency in treating back pain was reflected. Nevertheless, for suggesting RM as an option for management aimed at treating back pain, the evidence is inadequate, this review does determine the requirement for prospective data looking at back pain metrics as a particular outcome measure prior to and after RM.