Brown JA, Jackson BS, Burton CR, et al. - Researchers examined patients with bipolar disorder with psychosis (BDP) vs bipolar disorder with no psychosis (BDNP) to see if the portions of white matter differ between bipolar and healthy groups or between bipolar sub‐groups. They assessed diffusion‐weighted imaging data obtained from participants with BDP (n = 45), BDNP (n = 40), and healthy comparisons (HC) (n = 66). In comparisons between both bipolar groups and HC, minimal differences were identified in fractional anisotropy (FA) and radial diffusivity (RD) in localized portions of the left cingulum and corpus callosum, while there were more widespread reductions in spin distribution function (SDF). No differences in bipolar sub‐groups were observed on FA, RD, or SDF metrics. The results suggest that the identified white matter pathology is linked with the affective disturbance common in patients with bipolar disorder rather than the psychotic features unique to some.