Red blood cell distribution width for predicting significant liver inflammation in patients with autoimmune hepatitis
European Journal of Gastroenterology & Hepatology Nov 15, 2019
Wang H, Wang J, Huang R, et al. - Via involving 92 consecutive autoimmune hepatitis (AIH) patients who had a liver biopsy during 2016–2017, researchers explored the connection between red blood cell distribution width (RDW) and severity of liver inflammation in AIH. Using the Scheuer scoring system, liver histology was evaluated. For AIH patients with significant inflammation, the level of RDW was higher than in patients with mild inflammation. The level of RDW was positively correlated with the grades of inflammation of the liver. In predicting significant inflammation, the area under the receiver operating characteristic curve of RDW was 0.739, with 67.80% sensitivity and 75.76% specificity. RDW's diagnostic performance was better than alanine aminotransferase and immunoglobulin G for significant inflammation. For anticipating significant liver inflammation in AIH, RDW can be a promising indicator.
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