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Recurrent ischemic stroke: Incidence, predictors and impact on mortality

Acta Neurologica Scandinavica Apr 05, 2019

Khanevski AN, et al. - In this prospective cohort study, researchers assessed the incidence of recurrent ischemic stroke (IS) or TIA (n = 1,872), recurrence factors, and determined the effect of recurrence on all-cause mortality in a hospital-based stroke population in Western Norway. They used Multivariate Cox models to study recurrence factors and mortality. Two hundred twenty patients had 277 recurrent IS or TIAs during follow-up. Data revealed that the cumulative recurrence rate was 5.4%, 11.3% and 14.2% at 1 year, 5 years, and the end of follow-up, respectively. Findings suggested an independent association of hypertension, prior symptomatic stroke, chronic infarcts on MRI and age with recurrence. During follow-up, a total of 668 (35.7%) patients died. All-cause mortality was significantly increased by recurrence. There was modest risk of recurrent IS stroke or TIA in this population and it was linked to risk factors previously identified. All-cause mortality was more than doubled by recurrence.

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