Sweed MS, et al. - Researchers investigated the efficacy of the adjuvant use of misoprostol and oxytocin in decreasing intra-operative blood loss in cesarean delivery via administering either 400-μg misoprostol rectally or sublingually or placebo before cesarean section together with 5-IU oxytocin IV in a double-blinded randomized clinical trial including 636 term pregnant woman scheduled for cesarean section at Ain Shams University Maternity Hospital, Cairo, Egypt, between February 2013 and February 2014. Outcomes support that for decreasing intra-operative blood loss during cesarean section, misoprostol with oxytocin is an effective drug-combination with clinical superiority to sublingual over rectal route.