Martinez DA, et al. - Authors aimed to characterize the early follow-up changes of nevus-associated melanomas (NAMs) and to differentiate them from those observed in de novo melanomas (DNMs) for the earlier recognition of NAMs. They detected significant differences, distinguishing NAMs from DNMs, particularly while considering both baseline signs and follow-up changes. A help in defining the subgroup of high-risk patients, for whom comprehensive image monitoring could be beneficial was provided by the earlier identification of NAMs and their subsequent improved histological characterization.