Bansal A, Lee WW, Felfeli T, et al. - Researchers conducted this prospective case series to evaluate the in vivo physiology of retinal reattachment in humans using swept-source optical coherence tomography (SS-OCT) in real-time. Participants in the study were 15 consecutive patients with fovea-involving rhegmatogenous retinal detachment undergoing pneumatic retinopexy (PnR). SS-OCT was conducted at presentation and frequent intervals immediately following PnR. At the median follow-up duration of 13 weeks (IQR 7.5-18.0), 93.3% (14/15) achieved successful reattachment. This research characterizes retinal reattachment in vivo physiology in humans using high-resolution SS-OCT that occurs in five specific stages. The post-operative anatomic abnormalities were characterized by delayed progression through certain stages.