Re-examining the 1-mm margin and submucosal depth of invasion: A review of 216 malignant colorectal polyps
Virchows Archiv Jan 16, 2020
Berg KB, et al. - Researchers performed a retrospective cohort of 216 malignant polyps from 213 patients distinguished through the British Columbia Colon Screening Program. In only 43% of individuals, complete pathologic reporting (reporting of tumor grade, lymphovascular invasion, margin status, and tumor budding) was present. In this study, 61 patients had no poor prognostic factors on polypectomy, and 23 (37%) of those underwent surgery. At cautery, a positive margin cutoff of tumor indicated significantly elevated rates of lymph node metastases compared with a margin of greater than 0 mm, and polyps with a margin of greater than 0 mm had no risk of residual carcinoma. For positive margin and submucosal depth, adoption of submucosal depth and refinement of the cutoffs have the potential to distinguish high-risk patients and decrease the number of surgeries needed in patients with malignant polyps, they admitted that, a group that continues to grow significantly in part due to the introduction of colon screening programs.
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