Lassen MCH, et al. - In 432 acute coronary syndrome (ACS) patients who had echocardiography post-percutaneous coronary intervention (PCI), researchers assessed prediction of heart failure (HF), acute myocardial infarction (AMI) and death due to cardiovascular disease (CVD) by evaluating the ratio of early mitral inflow velocity (E) to early diastolic strain rate (E/e'sr). Participants were followed-up for a median duration of 4.4 [IQR: 0.2-6.3] years for the composite of HF, AMI, and death due to CVD. Overall 199 (46.1%) met the composite outcome. Following multivariable adjustment for demographic and clinical parameters, the composite outcome was still independently predicted by E/e'sr. Significant prognostic value of E/e'sr with regard to cardiovascular morbidity and mortality was evident in this patient populace. However, E/e'sr was not identified as an independent predictor over that of echocardiographic parameters. As opposed to patients with impaired systolic function, the prognostic ability of E/e'sr was stronger in patients with relatively preserved systolic function.