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Rating of four different foods in women with hyperemesis gravidarum: A randomised controlled trial

BMJ Open May 18, 2021

Ni Tan G, Tan PC, Hong JGS, et al. - Researchers conducted this prospective, randomised, within-subject cross-over trial to assess four foods in women with hyperemesis gravidarum (HG) on their agreeability and tolerability. Seventy-two women were selected and analyzed within 24-hour of their first admission for HG who were 18 years or older and had a confirmed clinical pregnancy of less than 16 weeks’ gestation. Women who were unable to consume food due to extreme symptoms, known taste or swallowing disorder were excluded. Every participant chewed and swallowed a small piece of apple, watermelon, cream cracker and white bread in random order, and was examined for 10 minutes after each tasting followed by a 2-minute washout for mouth rinsing and data collection. When tasted by women with HG, sweet apple had the highest agreeability score, the lowest nausea severity and intolerance–emesis response rate. The performance of white bread was consistently poor.

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