Alam M, Kakar R, Dover JS, et al. - Experts aspired to explore whether filler-associated vascular occlusion events of the face occur more often with injections performed with needles than with microcannulas. In total, 370 dermatologists (mean [SD] years in practice, 22.3 [11.1] years) participated and reported 1.7 million syringes injected. According to this retrospective cohort study, filler injections with either needles or cannulas were linked to a very low risk of intravascular occlusion events. In addition, the vast majority of such events were minor and resolved without scar or other injury. Injections with microcannulas were less frequently linked to occlusion events than injections with needles. After the first few years of clinical practice, the risk of occlusion per syringe tended to decrease and was also lower for those who injected fillers more often. Patient factors, anatomic site, and the type of defect being treated can depend on whether a needle or cannula is most suitable for injection.