Kim TO, Ahn JM, Kang DY, et al. - Given high risks of ischemic events and death during follow-up have been reported among patients undergoing myocardial revascularization for significant left main coronary artery disease (LMCA), so, researchers investigated the independent correlates for very long-term results post-LMCA revascularization, which would have clinical utility for risk stratification in such high-risk cases. From the MAIN-COMPARE registry, 2,240 patients with LMCA disease were assessed. The composite of all-cause mortality, Q-wave myocardial infarction, or stroke was the primary outcome. The 10-year rates of the primary composite outcome, all-cause mortality, and target-vessel revascularization (TVR) were estimated to be 24.7%, 22.2%, and 13.6%, respectively. In the entire study sample, independent correlates of the primary outcome were: age > 65 years, diabetes, prior heart failure, cerebrovascular disease, peripheral arterial disease, chronic renal failure, atrial fibrillation, ejection fraction < 40%, and distal LMCA bifurcation disease. Many clinical, as well as anatomic parameters, were also recognized as independent correlates of all-cause mortality and TVR. In interaction analysis, findings revealed no heterogeneities of the influences of variables based on revascularization type.