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Rate, risk factors, and outcomes of nonadherence in pediatric patients with celiac disease: A systematic review

Clinical Gastroenterology and Hepatology Jul 15, 2019

Myléus A, et al. - In this systematic review involving 7850 children, researchers studied the rate of adherence to a gluten-free diet (GFD) in celiac disease children, risk factors that affect adherence, and outcomes of non-adherence. For this investigation, they incorporated observational studies of ≥50 children diagnosed with celiac disease and recommended for placement on a GFD. In the final analysis, 49 of 703 studies were included. Substantial variation was found in adherence to a GFD among patients. The adherence rate was not connected with the adherence measurement method, therefore all techniques seem to be helpful, lacking agreement on the optimal metric. Studies are required to identify the best technique for ensuring long-term health compliance and impacts.
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