Li X, Deng Y, Wang J, et al. - Researchers examined how the Genotype® MTBDRplus line probe assay (LPA) for multidrug-resistant tuberculosis (MDR-TB) influence the total costs in a high-burden setting in China. In addition, they examined the performance of HAIN on smear-positive sputum and clinical isolates. They collected two sputum specimens from a total of 1,670 definitive TB patients at the Shandong Provincial Chest Hospital between May 2012 and May 2017 to conduct smear microscopy, conventional drug susceptibility testing (DST), and the HAIN test. Among these patients, smear-positive/culture-positive tuberculosis was reported in 1,307 (78.3%), and smear-negative/culture-positive tuberculosis was reported in the remaining 363 (21.7%). The HAIN test exhibited the sensitivity and specificity of 94.8% and 98.8%, respectively, for RIF resistance. The sensitivity and specificity were 89.5% and 95.6%, respectively, for INH resistance. These data demonstrate the accuracy of the HAIN test for detecting both RIF and INH resistance in TB patients. Using the HAIN test may lead to a lowering of healthcare costs and a decrease in the detection time for MDR-TB patients in China, despite the heightened costs for laboratory testing.