Cullen BM, et al. - A randomized controlled trial are conducted to evaluate healing outcomes in venous leg ulcers (VLUs) treated with a combination of collagen, oxidized regenerated cellulose, and silver in conjunction with standard of care (SOC; intervention group) compared with SOC alone (control group). The outcome of the current study showed that the standard of care included ADAPTIC nonadhering dressing (Acelity, San Antonio, Texas) and compression. Although the results were not important, there was a trend toward faster healing in the intervention group. The outcomes of this study indicate that collagen/oxidized regenerated cellulose/silver is a suitable and safe adjunctive intervention for use with SOC to manage VLUs.