Lee K, et al. - Researchers designed this trial to assess the effect of negative pressure wound therapy (NPWT) on surgical site infection (SSI) in closed groin wounds after lower extremity revascularization in patients at high risk for SSI. Findings revealed a nonsignificant lower rate of groin SSI in high-risk revascularization patients with NPWT compared with standard dressing. Owing to a lower than expected infection rate, the study was underpowered to detect a difference at the prespecified level. The NPWT group had markedly shorter mean hospital duration of stay compared with the standard dressing group.