El Lakis M, et al. - In this prospective cohort study, researchers evaluated the intraoperative techniques and thresholds that define positive lesions that warrant resection during Gallium 68 (⁶⁸Ga)-dotatate radioguided surgery (RGS). Between October 23, 2013, and February 14, 2018, 44 patients with neuroendocrine tumors (NETs) who had ⁶⁸Ga-dotatate RGS were included. Findings revealed that the lesions containing NETs had a higher tumor to background ratio (TBR) than those that did not contain NETs. The data presented in this work showed a TBR of 2.5 or more is a very sensitive threshold to indicate a lesion that is consistent with a NET on histological findings and therefore warrants surgical resection. Findings suggested that the omentum should be used as the background count activity for ⁶⁸Ga-dotatate RGS for abdominal NETs patients.