Mason RJ, et al. - This study attempted to assess perioperative and oncologic outcomes of patients undergoing radical cystectomy (RC) for recurrence of urothelial carcinoma (UC) after prior partial cystectomy (PC), and to compare these outcomes to patients undergoing primary RC. The data suggested that radical cystectomy after partial cystectomy is useful, without significantly adverse perioperative outcomes compared to patients undergoing primary RC. Nevertheless, the risk of death from bladder cancer may be higher, demonstrating the need for careful patient counseling prior to PC and the consideration of such patients for adjuvant therapy after RC.