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Radiation therapy impact on lymph node yield in patients with laryngeal squamous cell carcinoma

ENT Journal Apr 13, 2019

Reyes C, et al. - Researchers used a medical record database to assess if preoperative radiation therapy (RT) lowers lymph node yield (LNY) in patients with laryngeal cancers having surgery. They recorded that 44% of the 59 patients included had primary surgery, and 56% of subjects had salvage surgery. They noted 27.6 and 29.5 mean left and right total LNY in the salvage surgery group, respectively, while it was 32.2 and 33.7 for the primary surgery group, respectively. Both groups, when analyzed according to the site (glottic and supraglottic), side, and stage (III-IV), they observed no statistically significant difference in LNY in the student t test. Patients with prior RT may have had a lower mean of LNY, but our findings did not establish a statistically significant difference.

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