Racial disparities in uterine and ovarian carcinosarcoma: A population-based analysis of treatment and survival
Gynecologic Oncology Feb 14, 2020
Rojas C, Tian C, Powell MA, et al. - Researchers analyzed women in the National Cancer Database diagnosed with stage I-IV uterine carcinosarcoma (UCS) or ovarian carcinosarcoma (OCS) between 2004 and 2014, including non-Hispanic Black (NHB) and non-Hispanic White (NHW) women, to determine racial differences in UCS and OCS in Commission on Cancer-accredited facilities. NHBs vs NHWs more commonly had a diagnosis of UCS, and UCS diagnosis increased with age. OCS diagnosis continued to be < 5% in both races and all ages. NHBs with UCS or OCS were more often found in the South and had a greater chance of having a comorbidity score ≥ 1, low neighborhood income and Medicaid or no insurance. In NHB compared with NHW patients with UCS, the estimated risk of mortality was 1.38 following adjustment for demographic factors, and it declined by 4%, 16%, 7%, 19% and 10%, following sequential adjustment for comorbidity score, neighborhood income, insurance status, stage and treatment, respectively, leaving 43.5% of the racial difference in survival unexplained. Overall, in terms of characteristics, treatment and survival, there exist racial disparities in UCS and OCS with distinctions that justify an additional investigation.
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