Johnson HM, Shivalingappa H, Irish W, et al. - Researchers investigated how race influences endocrine therapy (ET)-associated shifts in volumetric breast density (VBD). This retrospective cohort analysis involved women with estrogen receptor-positive invasive breast cancer managed with ET. They applied Volpara software to determine VBD, the ratio of fibroglandular volume (FGV) to breast volume (BV). Higher rates of obesity and pre-menopausal status were observed among black women (n = 107) vs white women (n = 191). The groups showed similarity in terms of age- and BMI-adjusted baseline FGV, BV, and VBD. Similarity was also evident in modeled longitudinal changes: a follow-up of 30.7 ± 15.0 months (mean ± SD) revealed that FGV declined over time in premenopausal women, BV raised overall, and VBD reduced. A link was identified between higher BMI and lower baseline VBD. Overall, there seemed no influence of race on ET-associated longitudinal changes in VBD.