Fraccalvieri M, et al. – This study sought to formulate an optimal device to reduce discomfort of the patients and to heal wounds in the outpatient wound clinic. The Rexon–age–based therapy could considerably ameliorate and accelerate the healing process of chronic wounds. Despite being conducted in a small number of patients, this research consistently yielded positive effects on both the clinical aspect of the lesions, which underwent size reduction and wound reactivation and the quality of life of patients due to long–term pain relief.