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Pure pediatric ovarian immature teratomas: The French experience

Pediatric Blood & Cancer Jan 30, 2020

Pavone R, Dijoud F, Galmiche L, et al. - Utilizing Norris grading and International Federation of Gynecology and Obstetrics staging system, researchers sought to portray characteristics and outcomes of pediatric ovarian immature teratomas (IT) to better define the place of chemotherapy. Thirty-six cases have been identified with a median age of 11 years (range = 1-18): 35 of 36 stage I (17 stage IA, 13 stage IC, and 5 stage IX), involving seven patients with gliomatosis peritonei (GP), and 1 stage IIIB (IT peritoneal implants). Data reported that 5-year event-free survival and overall survival were 94% and 100%. The current series verifies the excellent prognosis of pediatric ovarian IT, arguing even in ruptured tumors for conservative surgical approach in GP and against systematic adjuvant chemotherapy.
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