Moura MC, Navin PJ, Johnson GB, et al. - Between 1999 and 2018, researchers performed a retrospective computer-assisted search for individuals with primary Sjögren's Syndrome (pSS) who were encountered at the institution and had histologically defined pulmonary nodule(s)/mass (es) (PNs). This study included a total of 41 individuals with pSS and PNs, the median age was 67 years (IQR, 56–74), 94% were women, and 39% had a smoking history. In patients with pSS, the majority of biopsied PNs were malignant, most commonly lymphomas. It was shown that smoking exposure, solitary nodule, and high FDG avidity were more frequently correlated with lung carcinoma. In patients with pSS, the clinical context, CT, and ¹⁸FDG-PET are complementary in the evaluation and management of PNs.