Pulmonary function and respiratory health after successful treatment of drug-resistant tuberculosis
International Journal of Infectious Diseases May 04, 2019
Vashakidze SA, et al. - In order to ascertain the post-treatment morbidity in patients with drug-resistant tuberculosis (DR-TB), researchers performed a cross-sectional study of 58 patients (median age 31 years) from Tbilisi, Georgia with cavitary DR-TB who were cured. Among these, 40% used tobacco, 59% had prior TB, and 47% underwent adjunctive surgical resection. Patients with multi/extensively drug-resistant tuberculosis (M/XDR-TB) may have lung damage following successful treatment; high risk for post-treatment lung damage could be assessed using chest X-ray. Respiratory symptoms at follow-up were reported less among those having adjunctive surgery. The TB subjects showed close correlation of the St. George Respiratory Questionnaire and spirometry results. More satisfactory medical care and pulmonary rehabilitation are needed for M/XDR-TB patients.
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