George A, et al. - In the present work, researchers examined the association of psychotropic medication use (any, typical antipsychotics, atypical antipsychotics, lithium) with invasive and in situ breast cancer risk among Women's Health Initiative participants (N = 155,737); they estimated hazard ratios (HR) and 95% confidence intervals (CI) for the association. A low prevalence of psychotropic medication use was reported (n = 642; 0.4%). Development of 10,067 invasive and 2,285 in situ breast cancer were reported during an average 14.8 (SD 6.5) years of follow-up. As per findings, there appeared no association between psychotropic medication use and invasive breast cancer risk. "Typical" antipsychotics appeared correlated with an elevation in in situ breast cancer risk which could not be explained by differences in screening mammography utilization.