Pan KY, Xu W, Mangialasche F, et al. - In this study, researchers examined the association between job demand–control–support combinations and trajectories of disability in later life. In addition, they explored the role of cognitive decline and the co-occurrence of chronic diseases in mediating this association. They examined a cohort of 2,937 individuals aged 60 years and older for the association of psychosocial working conditions with the rate of disability progression over 12 years. In all, they noted a link between unfavorable psychosocial working conditions during working life and the progression of disability in later life. This association, they found, was partially related to the decrement in cognitive function and increase in chronic-disease burden, and especially the former. Findings emphasized the significance of social support at work in a high-strain work environment, given its capacity to attenuate the impact of high-strain jobs on disability accumulation.