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Psychosocial long-term outcome in patients with psychogenic non-epileptic seizures

Seizure - European Journal of Epilepsy Sep 26, 2020

Walther K, Volbers B, Erdmann L, et al. - In the present study, the researchers sought to assess psychosocial long-term outcome in patients diagnosed with psychogenic nonepileptic seizures (PNES) and to anticipate follow-up results of PNES, economic status, and quality of life (QoL). Patients diagnosed with PNES were contacted by phone 1-16 years after communicating the diagnosis in the video-EEG-monitoring unit at the Epilepsy center between 2002-2016. Of the 70 non-comorbid epilepsy PNES patients (age: 41.1 ± 13.5 years; 74% female, follow-up: 5.2 ± 4.2 years), 23 patients (33%) have been confirmed to be PNES-free in the last 12 months. In multiple regression models, PNES cessation was only predicted by younger age at onset, whereas good economic outcome was determined by younger age and good economic status at diagnosis and PNES cessation at follow-up. In patients with PNES, the long-term outcome remains low and the majority of patients continue to have PNES. Good economic outcome, mood, and QoL were correlated with the PNES cessation.

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