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Psoriatic patients with chronic viral hepatitis do not have an increased risk of liver cirrhosis despite long-term methotrexate use: Real-world data from a nationwide cohort study in Taiwan

Journal of the American Academy of Dermatology May 14, 2018

Tang KT, et al. - Experts intended to analyze the impact of long-term methotrexate (MTX) use on the risk of chronic viral hepatitis-related cirrhosis among psoriatic patients in Taiwan. They selected psoriatic patients with chronic hepatitis B (CHB) (370 MTX users and 2047 MTX non-users) and psoriatic patients with chronic hepatitis C (CHC) (174 MTX users and 953 MTX non-users) from January 1, 2000 to December 31, 2010. Yielded data demonstrated that long-term MTX use was possibly not related to an increased risk of liver cirrhosis among psoriatic patients with chronic viral hepatitis.
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