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Psoas muscle size as a magnetic resonance imaging biomarker of progression of pancreatitis

European Radiology Feb 16, 2020

Modesto AE, Stuart CE, Cho J, et al. - The present study was conducted to evaluate psoas muscle size in individuals following the first episode of acute pancreatitis (FAP), recurrent acute pancreatitis (RAP), and chronic pancreatitis (CP), as well as its associations with pro-inflammatory cytokines. Researchers enrolled a sum of 145 individuals. There was a significant downward trend in psoas muscle volume between healthy controls and individuals following FAP, RAP, and CP in all adjusted models. In all models, it was shown that leptin was significantly correlated with psoas muscle volume. They found a reduction in psoas muscle size along the continuum from FAP to RAP to CP. Leptin seems to be one of the factors involved in this. In order to examine the association between skeletal muscle and inflammation of the pancreas, future research is warranted.
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