Chen Z, et al. - In this case-control study, the researchers assessed the occurrence rate of the internal carotid artery pseudo-occlusion (ICA-PO) on 4-dimensional–computed tomography angiography and examined its association with clinical outcome after reperfusion therapy. Between June 2009 and February 2017, the prospectively collected database was retrospectively reviewed for consecutive acute ischemic stroke patients who received reperfusion therapy. They used binary logistic regression to study the connection of ICA-PO with poor outcome and the rate of reperfusion, respectively. Data displayed that four dimensional-computed tomography angiography was a useful noninvasive technique to identify ICA-PO. Findings revealed that patients with ICA-PO were prone to undergo poor outcome from reperfusion therapy, particularly when reperfusion was not achieved.