Wadhwa A, et al. - Researchers mailed a cross-sectional, 23-item survey to practicing primary care providers (PCPs) affiliated with a tertiary children's hospital to assess their comfort levels in providing acute medical care to patients with childhood cancer who currently were undergoing therapy (on-therapy patients) and health maintenance care to childhood cancer survivors, independently and in collaboration with pediatric oncologists, along with confidence levels concerning knowledge about immunizations for survivors. They measured all levels using 7-point Likert scales. Of 402 eligible PCPs, 259 responded to the survey. PCPs reported a higher mean comfort level when conjugated with a pediatric oncologist in accommodating acute medical care for on-therapy patients and health maintenance care for childhood cancer survivors compared with independently providing such care. For acute care, PCP comfort in providing care in conjunction with a pediatric oncologist was identified to be associated with factors such as rural location compared with urban location and having cared for ≥ 6 on-therapy patients within the past year vs none. For survivor health maintenance care, PCP comfort was only associated with practice location < 50 miles from pediatric oncology specialty care vs ≥ 50 miles was the only factor. These findings thereby emphasize the necessity for collaboration between pediatric oncologists and PCPs when caring for children with cancer across the spectrum of care.