Jin MC, Harris JP, Sabolch AN, et al. - In this investigation involving 175,088 head and neck squamous cell carcinoma (HNSCC) patients, researchers used multivariable logistic regression to ascertain if radiotherapy (RT) modality (proton vs photon) was correlated with differences in the time to initiation of RT. For patients diagnosed with non-metastatic HNSCC between 2004 and 2015, who received either proton or photon RT as part of their initial treatment, the National Cancer Database was queried. They identified HNSCC patients receiving either photon or proton RT. According to findings, the use of proton therapy in both the definitive and adjuvant settings for HNSCC patients is correlated with delayed RT and may be related to poorer outcomes.