Su VY, et al. - Using data from Taiwan’s National Health Insurance Research Database, researchers performed a nationwide population-based study to assess the effect of antacid therapy for patients with chronic obstructive pulmonary disease (COPD) and gastroesophageal reflux disease (GERD). Participants included individuals with COPD with and without GERD. The researchers analyzed 3,485 patients with COPD and symptomatic GERD and 13,938 patients with COPD alone, and covered 12,806.57 and 56,809.78 person-years, respectively, from 2000 to 2011. Findings revealed a lower risk of acute exacerbation and mortality in correlation with the use of proton pump inhibitors among patients with COPD and symptomatic GERD.