Zirk-Sadowski J, et al. - Researchers aimed at estimating associations between long-term use of proton pump inhibitors (PPIs) and pneumonia incidence in older adults in primary care. PPI prescription was noted to be associated with greater risk of pneumonia in the second year of treatment in this large cohort of older adults. Results were robust across alternative analysis approaches. They recommended not considering the controversies about the validity of reported short-term harms of PPIs while considering potential long-term effects of PPI prescriptions on older adults.