Mahal BA, et al. - The focus of this investigation was prostate cancer–specific mortality in black vs nonblack men with Gleason scores of 6 vs 7-10.

• This was a cohort study.
• SEER Prostate Active Surveillance/Watchful Waiting data was used.
• Prostate cancer outcomes can be best predicted, independently, by the Gleason score.
• No definitive treatment is necessarily required in Gleason 6 disease, and this is the main distinctive feature between Gleason 6 disease vs Gleason 7 to 10 disease.
• Nevertheless, there is less clarity with regard to the implications of Gleason score in black men, this is attributed to disparate prostate cancer outcomes, this has been specifically seen for Gleason 6 disease, in which risk assessment and management of disease in black men is controversial.