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Prospective comparison between DCE-MRR and 99mTc-DTPA-based SPECT for determination of allograft renal function

Journal of Magnetic Resonance Imaging Aug 17, 2018

Wan-Li Z, et al. - Researchers performed this study on 70 kidney-transplant recipients, to prospectively compare dynamic contrast-enhanced MR renography (DCE-MRR) with 99mTc-DTPA-based single-photon emission computed tomography (SPECT) for determination of allograft renal function. They found that DCE-MRR using JZ2C (a modified two-compartment model) displayed the best overall performance, with a Pearson correlation coefficient of 0.81, a bias of –10.58 mL/min/1.73 m2, and a precision of 14.61 mL/min/1.73 m2, as well as high accuracy. Overall, they concluded that DCE-MRR using JZ2C better determines allograft renal function, compared to 99mTc-DTPA-based SPECT.
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