O'Bryan LJ, et al. - Researchers undertook this retrospective observational analysis to describe the use as well as the impact of prophylactic platelet transfusions among critically ill thrombocytopaenic patients, contrasting cases with or without bone marrow failure as a cause of thrombocytopaenia. Admissions to three ICUs in the UK were included. There were 11,757 admissions, of those, 399 (3.4%) patients received a platelet transfusion for thrombocytopaenia. Compared with the recommendations by guidelines, platelet transfusions were delivered at a higher median platelet count. A lower threshold for transfusion and a smaller increase in platelet count were reported among patients with bone marrow failure vs those without marrow failure.