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Prophylactic antibiotic use following cardiac arrest: A systematic review and meta-analysis

Resuscitation May 17, 2019

Couper K, et al. - Researchers examined how prophylactic/ early antibiotics (intervention group) vs clinically driven/ delayed antibiotics (control group) influence patient and infectious outcomes in adult cardiac arrest patients admitted to hospital. Searching MEDLINE (1946-current), EMBASE (1947-current) and the Cochrane library (inception-current) on 8th May 2018, they identified 6825 citations; of these, they included ten citations containing 11 studies (3 randomized controlled trials, 8 observational studies) for this work. Antibiotic prophylaxis following cardiac arrest was not identified to be associated with an increase in survival, survival with good neurological outcome, critical care length of stay or incidence of pneumonia.
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