Prolonged mechanical ventilation after left ventricular assist device implantation: Risk factors and clinical implications
ESC Heart Failure Mar 19, 2019
Papathanasiou M, et al. - Researchers investigated predictors of prolonged mechanical ventilation (PMV) post-left ventricular assist device (LVAD) implantation, and studied its clinical implications in 139 patients (mean age: 58 years; 84% male). Invasive ventilation > 7 days after LVAD implantation defined PMV. Predictors of PMV were determined via multivariable logistic regression analysis. The investigators used the Kaplan–Meier method to determine the survival. Among patients who underwent LVAD implantation, nearly half were affected by PMV post-procedure. Factors association with an increased risk for PMV included previous sternotomy, renal function, and platelet counts. Decreased survival at 180-day post-implantation and longer hospitalizations were observed in relation to PMV.
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