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Prolonged antibiotic prophylaxis after thoracoabdominal esophagectomy does not reduce the risk of pneumonia in the first 30 days: A retrospective before-and-after analysis

Infection Jun 11, 2018

Hochreiter M, et al. - Experts evaluated whether or not the prolonged antibiotic prophylaxis beyond a single perioperative dose was advantageous in preventing pulmonary infection after thoracoabdominal esophagectomy. The effect of a 5-day postoperative course of moxifloxacin, which is a frequently used antimicrobial agent for pneumonia, on the incidence of pulmonary infection and mortality after thoracoabdominal esophagectomy was assessed. The incidence of pulmonary infection was not seen to decrease with a preemptive 5-day postoperative course of moxifloxacin and no improvement in the mortality after thoracoabdominal esophagectomy was seen.
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