Liu L, Edmunds B, Takusagawa HL, et al. - By performing this prospective cross-sectional analysis, researchers employed projection-resolved optical coherence tomography angiography (PR-OCTA) to recognize plexus-specific peripapillary retinal perfusion defects in glaucoma. They used 4.5-mm OCTA scans centered on the disc in order to scan one eye each of 45 perimetric glaucoma participants and 37 age-matched normal participants. Using the PR-OCTA algorithm, flow projection artifacts in OCT angiograms were eliminated. An analysis of nerve fiber layer plexus (NFLP), ganglion cell layer plexus (GCLP), superficial vascular complex (SVC [NFLP + GCLP]), deep vascular complex, and all plexi combined, was performed. Findings revealed a more pronounced decrease in perfusion in superficial layers of the peripapillary retina (NFLP and SVC), vs in the deeper layers, in this glaucoma group. The possible usefulness of reflectance-compensated capillary density and vessel density parameters for both NFLP and SVC was suggested for the clinical management of glaucoma.