Researchers predicted cancer incidence rates and burden among adult persons living with HIV (PLWH) in the US through 2030. In this descriptive study, they reported that the cancer burden among PLWH was expected to shift, with prostate and lung cancer expected to emerge as the most common types by 2030.

Methods

• The HIV/AIDS Cancer Match Study projected cancer rates; HIV Optimization and Prevention Economics model projected HIV prevalence.
• Participants were HIV-infected adults.
• Cancer rates and burden among HIV-infected adults in the US by age for AIDS-defining cancer (ADC)—that is, Kaposi sarcoma, non-Hodgkin lymphoma, and cervical cancer—and certain types of non–AIDS-defining cancer (NADC) were projected for 2006 to 2030.
• They combined all other cancer types.

Results

• In 2010 to 2030, the proportion of adult PLWH in the US aged 65 years or older is projected to increase from 8.5% to 21.4%.
• They reported that age-specific rates were projected to decrease through 2030 across age groups for Kaposi sarcoma, non-Hodgkin lymphoma, cervical cancer, lung cancer, Hodgkin lymphoma, and other cancer types combined, and among those aged 65 years or older for colon cancer.
• Data revealed that prostate cancer rates are projected to increase.
• They observed that the estimated total cancer burden in PLWH will decrease from 8,150 cases in 2010 (2,730 of ADC and 5,420 of NADC) to 6,690 cases in 2,030 (720 of ADC and 5,980 of NADC).
• Prostate cancer (n = 1,590) and lung cancer (n = 1,030) are projected to be the most common cancer types in 2030.