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Proinflammatory and angiogenesis-related cytokines in vitreous samples of highly myopic patients

Cytokine Oct 31, 2020

Wei Q, Zhuang X, Fan J, et al. - Researchers conducted the study for determining the concentrations of vitreous proinflammatory cytokines and angiogenesis-related growth cytokines in highly myopic (HM) patients and controls. During vitrectomy for rhegmatogenous retinal detachment, myopic retinoschisis, idiopathic epiretinal membrane, or macular hole, vitreous humor (VH) was obtained from patients. According to results, 78 VH samples were obtained from 78 patients (36 HM vs 42 controls). Proinflammatory cytokines and angiogenic growth factors have been elevated in the VH of HM patients, indicating that an elevated inflammatory status and higher levels of angiogenic factors are present in HM eyes.

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